trimestatin


Organism:Protobothrops flavoviridis
Taxonomy:
Uniprot ID:P21859
PDB ID:1J2L
Mass:7682.68
Length:70
Sequence:P21859.fasta


LigandActivitiesIC50Cell linesReferences
fibronectin, vitronectin, fibrinogen, thrombin and collagenInhibits fibrinogen interaction with platelets. Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Controlling platelet aggregation and anti-angiogenesis cancer. PMID: 14499613