barbourin
| Organism: | Sistrurus miliarius barbouri |
| Taxonomy: | |
| Uniprot ID: | P22827 |
| PDB ID: | |
| Mass: | 7,701 |
| Length: | 73 |
| Sequence: | P22827.fasta |
| Ligand | Activities | IC50 | Cell lines | References |
| fibronectin, vitronectin, fibrinogen, VWF, TSP | Inhibitor of ligand binding to the integrins alpha-Iib/beta-3. Competition with fibrinogen for the RGD recognition sites on the alpha-IIb/beta-3 integrin results in the inhibition of platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. | 309 ±128nM | Platelet rich plasma | PMID: 7617961 PMID: 10815769 PMID: 2033037 |