Tergeminin


Organism:Sistrurus tergeminus
Taxonomy:
Uniprot ID:P22828
PDB ID:
Mass:7,671
Length:73
Sequence:P22828.fasta


LigandActivitiesIC50Cell linesReferences
Fibronectin, vitronectin, fibrinogen, VWF, TSP, FGF-2Inhibits fibrinogen interaction with platelets. Acts by binding to alpha-IIb/beta-3 on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Platelet aggregation : 192 ± 73 nM Human platelets in platelet-rich plasma, PMID: 2033037