Rhodostomin(Kistrin)


Organism:Calloselasma rhodostoma
Taxonomy:
Uniprot ID:P30403
PDB ID:3UCI
Mass:7847.85
Length:72
Sequence:P30403.fasta


LigandActivitiesIC50Cell linesReferences
Fibrinogen, thrombin and collagenInhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors alpha-Iib/beta-3. Inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells. 0.2µMSaos-2 tumour cell-induced platelet aggregation (TCIPA)PMID: 7841039