Rhodostomin(Kistrin)
| Organism: | Calloselasma rhodostoma |
| Taxonomy: | |
| Uniprot ID: | P30403 |
| PDB ID: | 3UCI |
| Mass: | 7847.85 |
| Length: | 72 |
| Sequence: | P30403.fasta |
| Ligand | Activities | IC50 | Cell lines | References |
| Fibrinogen, thrombin and collagen | Inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors alpha-Iib/beta-3. Inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells. | 0.2µM | Saos-2 tumour cell-induced platelet aggregation (TCIPA) | PMID: 7841039 |