EMS11
| Organism: | Echis multisquamatus |
| Taxonomy: | |
| Uniprot ID: | P0C6A3 |
| PDB ID: | |
| Mass: | 7,469 |
| Length: | 68 |
| Sequence: | P0C6A3.fasta |
| Ligand | Activities | IC50 | Cell lines | References |
| Fibronectin, VCAM, MadCAM and Fibrinogen | Inhibitor of platelet aggregation. Inhibits the adhesion of both the alpha-4/beta-1 (ITGA4/ITGB1) and the alpha-5/beta-1 (ITGA5/ITGB1) integrins to VCAM-1 and fibronectin respectively with almost the same degree of specificity | 6.0 nM and 14 nM | K562 and Jurkat cells | PMID: 12667142 |