EC3


Organism:Echis carinatus
Taxonomy:
Uniprot ID:P81631
PDB ID:
Mass:7,424
Length:67
Sequence:P81631.fasta


LigandActivitiesIC50Cell linesReferences
Fibronectin, VCAM, MadCAM , (VCAM-1) (MadCAM-1) and FibronectinCalcium-dependent cell-adhesion protein inhibits human and murine alpha4 integrin and attenuates lymphocyte infiltration of Langerhans islets in pancreas and salivary glands in nonobese diabetic mice. EC3inhibited adhesion of cells expressing alpha4beta1 and alpha4beta7 integrins to natural ligands 6-30 nM, 150 nM and 500 nM.Mucosal addressin cell and vascular cell, K562 cells and Chinese hamster ovary cellsPMID: 10623633 PMID: 10212222